MEDICATION TYPE
Antibiotic
INDICATIONS
Treatment of respiratory tract exacerbations due to sensitive H.influenzae and Streptococcal infections.
DRUG INTERACTIONS
Allopurinol
Increased risk of rash with concomitant use.
Methotrexate
Increases methotrexate toxicity (reduced secretion).
Probenecid
Reduces penicillin excretion.
NOTES
Higher doses (e.g. 1 g tds) often used in CF due to altered pharmacokinetics.
MEDICAL WARNING
Amoxycillin should only be administered under the supervision of a healthcare professional. Always verify against current BNF and your local CF protocol before prescribing.