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Clofazimine
C
MEDICATION TYPE
Antibiotic
INDICATIONS
Treatment of Mycobacterium abscessus infections.
DRUG INTERACTIONS
Clofazimine
May reduce the absorption of rifampicin.
Isoniazid
May increase plasma and urinary concentrations of Clofazimine and decrease skin concentrations.
Increased risk of prolonged QT with other drugs that prolong QT eg. Fluoroquinolones.
NOTES
Counsel on reversible skin discolouration; ECG monitoring.
MEDICAL WARNING
Clofazimine should only be administered under the supervision of a healthcare professional. Always verify against current BNF and your local CF protocol before prescribing.