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Ivacaftor
I
MEDICATION TYPE
CFTR Potentiator
INDICATIONS
Treatment of Class III, IV and residual function CFTR mutations.
DRUG INTERACTIONS
Food and lifestyle
Avoid bitter (Seville) oranges as they are predicted to increase the exposure to Ivacaftor.
NOTES
Take with fat-containing food. Monitor LFTs.
MEDICAL WARNING
Ivacaftor should only be administered under the supervision of a healthcare professional. Always verify against current BNF and your local CF protocol before prescribing.