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Urokinase
U
MEDICATION TYPE
Thrombolytic
INDICATIONS
Blocked central venous catheter (alternative to alteplase).
DRUG INTERACTIONS
Heparin
Increased risk of bleeding
Warfarin
Increased risk of bleeding
NOTES
Instilled volume sufficient to fill catheter lumen.
MEDICAL WARNING
Urokinase should only be administered under the supervision of a healthcare professional. Always verify against current BNF and your local CF protocol before prescribing.